Blackmores Mega B Complex

Be careful about B6 toxicity and muscle twitches (fasciculations) etc – I take a full supplement regime to do a number of things, including not being malnourished while dieting. And also sleep. Hence the B Complex - a way to get adequate vitamin B levels, including B6, which I was taking as it is supposed to assist with getting to sleep. I was taking B6 on its own in addition to this, and then just took the Mega B Complex.

I didn't realize that the RDA is 1.7mg and the amount typically provided in these is around 50mg. In B6 specifically, and in the B Complex. So it's more than 10x the recommended dose.

I noted that I was gradually getting increased twitches in my triceps and sometimes pectoral muscles. To the point where it was keeping me awake at night. I went to the doctor about it. It was only using an AI chatbot that I was able to diagnose the problem. Evidently the B6 can be excessive in amounts greater than 1g per day, and likely lower than that. A maximum of 12mg per day is allowed in the EU.

https://connect.mayoclinic.org/discussion/b-6-vitamin-danger/ https://www.ncbi.nlm.nih.gov/books/NBK554500/ https://www.easy-immune-health.com/vitamin-b6-toxicity.html

Symptoms over B6 toxicity generally resolve over time, but in some cases there can be permanent problems.

I stopped the supplementation of this about a month ago and gradually the fasciculations (involuntary twitching) in my triceps has ceased completely.

While I am writing this vs a Blackmores product, B6 is in a lot of products, including for sleep, and it is something that for susceptible people is a problem.

Some people are able to take less than 1000mg with no problems, but some (perhaps with the MTHR gene) are not able to. Perhaps for many people this product is ok, but not for me. That's why I've given it 3 stars - for me it is 1 star, but it likely has the correct dosages on the label, just that people should be careful about consuming, and it won't be immediate, it likely takes some time to accumulate toxic effects.

Ok, I've done my bit of public service on the subject of Vitamin B6 toxicity.