Profender for Cats
191 reviews
DO NOT USE!!! EVER! The worst product known to man kind. If you want your kitty alive and healthy. Stay as far away as possible from this absolute [Content Removed].
do not use this product it is poison and any veterinarian that would use this product to treat animals should be arrested for cruelty to animals i wish i could have known how bad this product is i trusted the vet i took my kitty too. i would think a licensed veterinarian would research the drugs there are injecting into there customers loved ones… Read more
before doing so.. in twenty min of researching this product i learned i would not prescribe it to the veterinarian that killed my cat.. 12\29\2025 i took my kitty of 14 years in for ear mites and she treated her with profender topical solution on 12\30\2025 she was showing hard breathing and drooling. 1\1\2026 9 am i rushed her to the are veterinarian hospital but she past on the way a horrible death crying in pain and she could not breath i could not drive any faster as my best friend of 14 yrs died in my lap. how is this product allowed to be used
My 3 month old foster kitten started labored breathing an hour after I applied profender between his shoulder blades. He struggled to breath, began crying out in pain, had a seizure and passed away. Do not use this stuff on kittens at the very least. Use extreme caution on older cats. Do a test-drop application before administration of the entire dose. RIP Griffin Show details
Reviews with attachments
THIS IS POISON – Almost killed my cat. She still won’t eat. She got dewormed on 1/9/25 with pro fender. The next day she would hardly eat. The day after that she wouldn’t eat at all and we walked in on her laying on the floor struggling to breathe. Luckily I’m a very natural minded person and have a stash of supplements. I mixed up a bowl of NAC and milk thistle… Read more
in water and started giving it to her via syringe and after that I gave her a bath in Epsom salt to detox her and wash off the excess dewormer. About 30 minutes later she started coming back and her breathing got better. As of now her breathing is normal. I got her to drink a tad on her own and eat a piece of ham on her own. I prayed and prayed for God to save my little girl. DO NOT USE THIS. I asked the vet if her symptoms could be a reaction to pro fender and ofcourse they said no. They’re just lying to cover themselves like doctors love to do. Imagine if I overloaded her system with all the crap they recommended my small kitten to receive? Luckily she got no shots that day or else her liver probably would have shut down completely. Reasearch the veterinary field. They want to make you a customer.
Another Profender negative review – I had no clue what Profender was or the possible side effects. I recently got an adorable kitten from a friend. She weighed 2.2 pounds at her 1st vet check and was treated for fleas. The vet gave me the dose of Profender to administer from a preloaded little tube 10 days later. At 10 pm i administered the medication and put her in her crate for… Read more
the night. (It has a litter box plus water and she goes into it on her own)
I got up in the morning and was surprised she didn’t ask me to come get her. She was laying in her crate and didn't jump up to greet me. I thought maybe she had an upset tummy from the worming. I sat her on my bed and she fell onto her face. She couldn’t use her R front paw. I was so scared and couldn't imagine how she could have hurt her leg.
I couldn’t get her into my regular vet so i took her to a pet urgent care. 430.00 later i had an antibiotic for her fever, xrays that showed no broken bones and no diagnosis. She didn't appear to be in any pain when they were checking out her leg.
I told the vet I’d given her Profender at 10 pm the night before. She didn't even comment on it. I wasn’t sure she heard me so again i mentioned it a bit later and again, she ignored me.
I googled reactions and it said “most” reactions clear up in 24-48 hours.
In 44 hours, she started to try to put a little weight on her leg and at 48 hours it was like it never happened. After reading through this sad stories, I know we are lucky it was brief!
This morning she was like she’d chugged an energy drink. It was wonder to have my spunky kitten back.
I will NEVER allow another cat of mine to receive Prefender. I will also never give a pet of mine a new medication at bedtime. Lesson learned the hard way!
Never again – My vet gave me pretender for my 5 Mo. Old... I never should have..... I applied it PROPERLY on Apr. 13th and on Apr 15th he had severe seizures and passed away in my arms.....my husband and I cried....we loved our little baby..... I'm not sure I can trust my vet anymore...... I really am going to go with natural and herbs for cats..... I miss Baby Boy so much... Show details
Positive reviews
Great product – I can't understand all of the one star and negative reviews about this product. I have been using profender for a couple of years and have never had an issue, in fact I believe it works really well. My Cats are healthy and have never had any problems with this product.
it worked & only Diarrhea occured – I rescued an alley cat who had worms and could not get her to take oral dewormer and I could not find the Bayer drontal worming pill anywhere…finally , a community low-cost clinic gave me this , it cost twenty $…so not as Inexpensive as the drontal but SO much easier to apply! Poor kitty has been through the ringer and I didn’t want to traumatize… Read more
hurt anymore. I was pretty scared after reading reviews, after I put it on her, but she didn’t have any noticeable reaction other than diarrhea. It’s been a week, maybe a little more since I put it on and a dead worm just came out in her poo…& the first day dying worms were expelled…so it can take a bit of time for it to work. i am hoping we do not need a second treatment. it says one treatment can be sufficient. she did not have Any loss of fur or any weird reactions that people are mentioning. She did go up once, but she did that before I applied the wormer also. It is important to put it on the back of their head! where they CANNOT LICK!
Needs to be applied correctly! – Some of these negative reviews make it sound like people are giving this to their cats orally. You put it on the back of their neck where they can’t lick it off. It gets absorbed through the skin. I foster cats and this works really well for getting rid of worms! I love the product and I’ve given it to at least a dozen cats with no issues. But it goes on the back of the neck!!! not in the mouth or anywhere a cat could lick it off! Show details
Negative reviews
Could have killed my cat – My cat threw up worms so we took her to her vet and they prescribed 2 doses of this for her. The first dose she was fatigued but other than that was herself. We put the second dose on a month later and for the last 4 days she has been crying in pain and unable to touch. She didn’t eat for 3 days and we’ve finally managed to get her to eat a mix of… Read more
wet and dry food and drink some water. She’s finally letting us touch her somewhat but only on her head and when we try to pet her sides or pick her up she begins hissing and trying to bite and claw us. This isn’t our girl, she’s always loveable and never bites or hissed even if she doesn’t want to be touched or doesn’t know you. Shes obviously in a ton of pain. We are washing it off of her today and thankfully for these reviews I’m hoping she becomes herself again. I don’t know why vets keep prescribing this if it is so dangerous for a cat’s health. Never again. There’s got to be a different way to treat a roundworm problem. And for anyone thinking I gave it to her oral or in a place that she could lick, it was put exactly where the vet applied it before. She didn’t ingest any of it.
Profender killed my cat,too – PROFENDER-- a topical medication used to treat internal parasites--is what killed my cat. He began a downhill decline almost immediately and died of a massive seizure six days after applying it . He was under vet care immediately. He was atwo year old,big,robust,healthy cat.
This stuff is poison – Made my 9year old male cat very sick. The vet applied it on him and I shouldn't have trusted them. On the way home he started panting and crying in pain. Thankfully he stopped and I have him food and water. I ended up washing the medicine off within a few hours because I had a bad feeling about it. I then found all these reviews of cats dying. I… Read more
made sure to clean him off better after reading everything. He was sleepy and out of it all night and this morning he looks more energetic now. I hope he isn't affected in the long run from this stupid poison.
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Recent reviews
Anna / Tux / reaction to profender – So I applied profender spot on to my 3.7 kg cat on Monday 11th November 2024 for medium cats 2.5kg/5kg so the correct dose ….. this is the second time I’ve applied and he’s had a reaction both times 1st time I wasn’t aware until I’ve put two and two together all I can say is this product needs to be stopped being produced as it seems to be… Read more
definitely toxic! The company vetoquinol need to look at the negatives and maybe research something else ! I’ll Not be using it ever again let’s just say I might not be so lucky to tell the story of the situation,,, I’ve been a vet nurse 21 years and this is my first ever complaint over a prescription veterinary wormer !
Profender killed our cat – Few hrs after applying profender. Our till then healthy and happy 3 year old cat developed seizures and bleeding and died within 10min. We are heartbroken. We have reported to AERP, please if you have experience any side effects report to your supplier and AERP. Show details
Terrible!!! – I will never give any of my pets profender again. I have two sick cats because of it. They never licked it. After putting it on Milo he became very lethargic, wouldnt eat, couldnt lift his head, very confused. We took him to the vet and they said it was rare. They gave him meds. We then put it on the female cat (mama) and she now is very sick. She… Read more
has been vomiting, cant eat, very lethargic and worried she will not make it. She now is on the same meds the vet gave Milo. Please do not put this on your cats. I read some reviews before but didnt listen. I hope my two get well and recover. I feel so bad for giving them something that is about to kill them.
Profender murdered my cat – After applying to my cat she appeared to not be able to swallow her own saliva and was sweating profussly and crying in agony breathing very hard and fast she became so exhausted that tongue was hanging out totally not able to even crawl and she screamed when I picked her up the worst scream of pain but then realized she was in her daddys arms and… Read more
we laid down together on the couch and she was rapid short breathes and then stopped and died in front of me and an older cat of mine who didnt have worms. I continued to sleep next to her not knowing the worst smelling bowel liquid came out of her butt all over the floor as I had to go out her in a cardboard box that i didn't bury right away in hopes she'd spring out of it magically, and then after i realized she really was dead i had to dig a hole in the back yard and bury her in the cardboard box, thanks Profender for cats
WARNING. This product could make your cat very sick – This product made our cat extremely sick. Shortly after using this product she became lethargic and very uncomfortable followed by daily vomiting and a loss of appetite. Within a few days she has lost half her bodyweight and refuses to drink or eat. Vet is not sure she will survive. DO NOT USE THIS PRODUCT!! Show details
Mau 4-5 month kitty broke out in hives – I was fostering a kitten Mau with three other kittens 4-5 months old. The Mau sweet kitten literally broke out like is he had hives it was just terrible. This paws particularly were inflamed, inflamed patches in the hand, arm and legs, he had a bald area exactly in the back of the neck where I put this profounder on him, I put the correct amount… Read more
because the vet prepared it for me. Some people I spoke to believed it was ringworm or a yeast infection, and it wasn’t either of those because the kitten was perfectly fine, and the profounder created a bald spot for this cat so this cat had a highly allergic or some type of reaction to this product and I personally will never after this experience with the one kitty use this product ever again. Went back to the same vet and he prescribe some type of multi-medicine that also is a cure for ringworm, it was I believe the week on a week off a week on a week off for 2 to 3 weeks. It’s been a couple of years now, so I can’t really recall the exact details. It took about a month for him to fully get healed and healthy again, but I definitely advised the rescue and anybody adopting this beautiful Mau kitten to never ever use this product on this cat. I felt so horrible to see him like that poor boy just happy all the inflammation this product caused him, finally started to decrease and his hair started growing back.
Bad Experience – My cat is/was a healthy 6 yo cat weighing 7lbs. She had roundworm and my vet recommended Profender. Inside a week she was down to 5.6lbs lethargic, won't eat much and seems to be thirsty a lot. She is in hiding in the bathroom. Not sure she is going to make it. Only thing different is the Profender. Even with the worms she was doing OK, still needed to get rid of them though. I am convinced this medicine is what has done this to her. Show details
DO NOT BUY THIS PRODUCT - Profender Allwormer killed our cat – AVOID AVOID AVOID - TOXIC TO CATS If I could give no stars I would, this product should be banned. We applied 1 dose of Allwormer completely as directed to an area behind our cat's head so he had no way of getting to it. The day after he began to show signs of poisoning ( we researched this product and found his symptoms matched so many others)… Read more
and on day 2 he was vomiting bile and liquid till day 3, went blind, verbalising pain, not eating or drinking, lost all energy and went outside to find somewhere to lay down and basically die and we thought he was a gonner. He remained like this until for 4 days not eating and barely keeping water down. My wife googled electrolytes for cats and made a honey based water, salt and bicarb mix that she has been syringing into his mouth to keep his fluids up as he laid almost comatose wherever he managed to crawl to. The irony is we took him to the vet the week prior for a checkup and they said he was in excellent condition for his 16yrs. Edit.. SadIy he did not recover and was starving to death so we had to put him down which broke our hearts.. DO NOT BUY THIS TOXIC GARBAGE.
My poor cat – A large lump of cat hair came off my 5 year old on her neck where I had put the Profender. I rang my vet, they said they had never heard of any bad effects. They wouldn’t reimburse for unopened pack. Do not use this Show details
Find out how Profender for Cats compares to other Heart & Intestinal Wormers
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3 month old kitten sick – Vet gave me this Profender dewormer for my 3 month old newly gotten kitten. After 24-36 hours she is not herself. Walking with back leg weakness, very lethargic, not eating or drinking, lower body tremors and she is a true lap cat cuddlier and does not want to be held now and hiding under the couch. Called vet, said to bring her in, gave her IV… Read more
fluids, fever of 104. Vet wouldn't even mention that it probably was this Profender. Cost me $185 for the visit and she is still sick.
Never again – Gave it to my cat on back of her neck. Became lethargic then threw up several hours later. I washed it off and she's eating so far but would not sleep with me all night which is unusual. Still mongering her but never again. I hope she'll be ok. Show details
I wish I never tried it – My cat developed weakness in legs next day after applying Profendro. Today is 5th day and still the same. And vets keep denying that is related with medication Show details
Serious side effects – As part of a vet health plan I used this product. The instructions did not warn that it could have serious neurological side effects by ingesting small dried product from the fur via grooming, despite it being applied at the back of the neck as per instructions. My cat was fit and well but 6 hours later vomited and back legs very unstable, yowling… Read more
and in distress. Taken to emergency vet where he still is after 24 hrs in drip etc. Remember to report side-effects via supplier or your animal medicine side effects dept via government so this product can be taken off shelves.
similar product – I note reviews that share concern about this product..I have had it suggested from our vet but a spoton that is similar in content is felpreva and this made my 17 year old cat extremely sick.. I washed it off in 15 hours and she recovered but there are no reviews so I just want to share the warning..It was correctly applied. Show details
Never again! – I have two cats, one is 14 and the other 13. My 14 year old started to loose weight so I took him to the vet for tests. I was told he had no illness or disease so they figured it was worms. They prescribed profender. I asked for a second treatment for my other cat for precaution. For my 14 year old it went very well. He is gaining his weight back… Read more
and is feeling much better. For my 13 year old it's been horrible. One hour after applying the profender treatment he started walking weird. After 2-3 days he would sleep longer than usual and stopped asking to go outside which is very unusual. After a week I noticed weakness in his legs, he now has trouble walking. He also cries when I touch him and constantly keeps his head down. He also started to hide under my bed which he never does and doesn't respond when I call his name. He stopped eating his hard food but his able to eat canned tuna and salmon. In the beginning he stopped drinking but I found a way to get him to drink by adding water to the tuna and salmon. I feel like I'm going to loose him I have never seen him in such a state. Tomorrow will be two weeks since I applied the treatment I hope he gets better soon.
Profender is deceiving. Class action suit up – I can't believe what I'm reading about the dangers of this terrible medicine. I should of looked more into the medication before applying on my girlfriends kitten whom she rescued and is only 3 months old. His name is Jack who is awesome and I tried holding him for an hour after applying the medication because I unknowingly put it in the wrong… Read more
spot because he kept trying to move but I ended up setting him down and he licked the area I put the medicine on and he was shaking non stop for about 20 minutes. I didn't know what to do so my girlfriend gave him a tiny bit of 2% milk. He been sleeping for an hour so I'm praying Nothing more happens but from all the negative reviews I'm extremely worried. You know what's crazy is that it says not to let your animals lick the area for an hour but doesn't say if it's okay after that hour. Not one article specifies if it's safe when that hour is up. Is it inactive after one hour or not. How could you promote a medication like this without specifying details like after an hour is up? Oh, yeah, I know why, because it's dangerous and you want to keep making money off a medication that is doing more harm than good. I'm praying for everyone's animals who were affected adversely from this medication.
Do not recommend – Used a smaller than recommended dose on 6 foster kittens. 2 of them stopped eating, became lethargic, had severe stomach bloat, and one has liver damage/failure. The other 4 kittens seem fine. I had used this one other time on a kitten with no problems. I would recommend something more gentle instead. I may loose 2 kittens. They are in critical… Read more
condition. I’m not positive its the profender but there was none of the critical symptoms prior to use. 4 kittens treated are fine.
Kills cats! – Reviewed this a year ago. I see people are still using this and from what I read, cats are still suffering. I don't know why this is still on the market. Please see my review from last year under catmom53. My kitty has been gone 11/2 years and I still cry often over her suffering for years after one application of this poison. Having my vet, a professional, blown off by the manufacturer, unconscionable. Please do not use, I beg you. Show details
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Sadly a week after posting this we had to put him down to prevent further suffering by him starving to death.